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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">radhyd</journal-id><journal-title-group><journal-title xml:lang="ru">Радиационная гигиена</journal-title><trans-title-group xml:lang="en"><trans-title>Radiatsionnaya Gygiena = Radiation Hygiene</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1998-426X</issn><issn pub-type="epub">2409-9082</issn><publisher><publisher-name>NIIRG</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">radhyd-102</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Научные статьи</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Scientific articles</subject></subj-group></article-categories><title-group><article-title>ИССЛЕДОВАНИЕ БИОКИНЕТИЧЕСКИХ ОСОБЕННОСТЕЙ МОДЕЛИ МЕТАБОЛИЗМА СТРОНЦИЯ-90 И ВОЗМОЖНОСТИ ОЦЕНКИ УРОВНЕЙ ПОСТУПЛЕНИЯ РАДИОНУКЛИДА ПО РЕЗУЛЬТАТАМ ИЗМЕРЕНИЯ АКТИВНОСТИ В МОЧЕ</article-title><trans-title-group xml:lang="en"><trans-title>INVESTIGATION OF BIOKINETIC PECULIARITIES OF STRONTIUM-90 METABOLISM MODEL AND POSSIBILITY OF AN ESTIMATION OF RADIONUCLIDE INTAKE LEVEL BASING ON THE RESULTS OF THE MEASUREMENTS OF ACTIVITY IN URINE</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Репин</surname><given-names>В. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Repin</surname><given-names>V. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Тел.: (812) 2327025</p></bio><email xlink:type="simple">v.repin@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Санкт-Петербургский научно-исследовательский институт радиационной гигиены имени профессора П.В. Рамзаева</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Saint-Petersburg Research Institute of Radiation Hygiene after Professor P.V.Ramzaev</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2013</year></pub-date><pub-date pub-type="epub"><day>16</day><month>08</month><year>2015</year></pub-date><volume>6</volume><issue>4</issue><fpage>5</fpage><lpage>10</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Репин В.С., 2015</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="ru">Репин В.С.</copyright-holder><copyright-holder xml:lang="en">Repin V.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.radhyg.ru/jour/article/view/102">https://www.radhyg.ru/jour/article/view/102</self-uri><abstract><p>В статье представлены результаты обоснования возможности использования возраст-зависимой биокинетической модели метаболизма 90Sr в организме человека для оценки средних уровней суточного поступления с рационом по результатам измерения содержания радионуклида в суточной пробе мочи. Показано, что для лиц различного возраста в условиях хронического поступления 90Sr темп его выведения с мочой определяется, в основном, за счет временных депо фиксации в мягких тканях и на поверхности кости, характеризующихся быстрыми скоростями обмена, и мало зависит от накопления радионуклида в объеме скелета. Кроме того, временные депо фиксации выполняют функцию усреднения уровней поступления радионуклида при уровнях суточного поступления, распределенных по времени случайным образом.</p></abstract><trans-abstract xml:lang="en"><p>An article presents the results of the substantiation of possibility of the use of age-dependent biokinetic model of 90Sr in a human body for estimation of the average levels of a daily intake with a diet by means of measurements of radionuclide activity in a daily urine sample. It is shown that for persons of different age groups in a case of chronic intake of 90Sr the rate of excretion with urine, basically, reflect by the temporary depots of radionuclide fixation in soft tissues and on a surface of the bone, and depends slightly on accumulation of radionuclide in the whole skeleton. Besides, temporary depots of radionuclide fixation fulfill the function of averaging of radionuclide intake in a case of daily intake levels, randomly timely distributed.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>модель метаболизма</kwd><kwd>стронций-90</kwd><kwd>поступление</kwd><kwd>выведение</kwd><kwd>особенности обмена</kwd></kwd-group><kwd-group xml:lang="en"><kwd>metabolism model</kwd><kwd>strontium-90</kwd><kwd>intake</kwd><kwd>excretion</kwd><kwd>peculiarities of exchange</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Age-dependent Doses to Members of the Public from Intake of Radionuclides – Part 2 Ingestion Dose Coefficients. ICRP Publication 67. Ann. ICRP 22 (3-4), 1992.</mixed-citation><mixed-citation xml:lang="en">Age-dependent Doses to Members of the Public from Intake of Radionuclides – Part 2 Ingestion Dose Coefficients. ICRP Publication 67. Ann. ICRP 22 (3-4), 1992.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Shampine, L.F. TheMATLAB ODE Suite / L.F. Shampine, M.W. Reichelt // SIAM Journal on Scientific Computing. – 1997. – V. 18. – Р. 1–22.</mixed-citation><mixed-citation xml:lang="en">Shampine, L.F. TheMATLAB ODE Suite / L.F. Shampine, M.W. Reichelt // SIAM Journal on Scientific Computing. – 1997. – V. 18. – Р. 1–22.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Shampine, L.F. Solving Index-1 DAEs in MATLAB and Simulink /L.F. Shampine, M.W. Reichelt, J.A. Kierzenka // SIAMReview. – 1999. – V. 41. – Р. 538–552.</mixed-citation><mixed-citation xml:lang="en">Shampine, L.F. Solving Index-1 DAEs in MATLAB and Simulink /L.F. Shampine, M.W. Reichelt, J.A. Kierzenka // SIAMReview. – 1999. – V. 41. – Р. 538–552.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
