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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">radhyd</journal-id><journal-title-group><journal-title xml:lang="ru">Радиационная гигиена</journal-title><trans-title-group xml:lang="en"><trans-title>Radiatsionnaya Gygiena = Radiation Hygiene</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1998-426X</issn><issn pub-type="epub">2409-9082</issn><publisher><publisher-name>NIIRG</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21514/1998-426X-2025-18-4-113-120</article-id><article-id custom-type="elpub" pub-id-type="custom">radhyd-1246</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Обзоры</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Reviews</subject></subj-group></article-categories><title-group><article-title>Ключевые аспекты декорпорации плутония и америция в случаях  их аварийного поступления персоналу радиационно опасных производств</article-title><trans-title-group xml:lang="en"><trans-title>Key aspects of decorporation of plutonium and americium in cases of emergency intake  by personnel of radiation hazardous production facilities</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6036-4178</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Соколова</surname><given-names>А. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Sokolova</surname><given-names>A. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Соколова Александра Борисовна - кандидат биологических наук, главный научный сотрудник, курирующий вопросы радиационной безопасности</p><p> Адрес для переписки: 456783, Челябинская область, Озерск, Озерское шоссе, д. 19</p></bio><bio xml:lang="en"><p>Alexandra B. Sokolova – Candidate of Biological Sciences, Chief Researcher in Charge of Radiation Safety Issues, Science </p><p>19, Ozyorskoe Shosse, Ozyorsk, Chelyabinsk Region, 456783</p></bio><email xlink:type="simple">sokolova@subi.su</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Южно-Уральский федеральный научно-клинический центр медицинской биофизики  Федерального медико-биологического агентства</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Southern Urals Research and Clinical Center for Medical Biophysics of the Federal Medical Biological Agency</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>10</day><month>01</month><year>2026</year></pub-date><volume>18</volume><issue>4</issue><fpage>113</fpage><lpage>120</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Соколова А.Б., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Соколова А.Б.</copyright-holder><copyright-holder xml:lang="en">Sokolova A.B.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.radhyg.ru/jour/article/view/1246">https://www.radhyg.ru/jour/article/view/1246</self-uri><abstract><p>В условиях производства по переработке плутония, несмотря на достигнутое улучшение радиационной обстановки на рабочих местах, не исключена вероятность аварийных ситуаций, приводящих к острому ингаляционному поступлению радионуклидов или их поступлению через поврежденные кожные покровы. В таких случаях для предупреждения радиационных поражений или уменьшения риска их возникновения применяют хелаты. Цель настоящего исследования – изучить отечественные и зарубежные методические документы и определить степень полноты и достаточности содержащихся в них рекомендаций по выполнению декорпорации плутония и америция хелатными комплексами. Были рассмотрены общие рекомендации по применению хелатных комплексов, представленные в Публикации № 96 Международной комиссии по радиологической защите, документы Международного агентства по атомной энергии, а также документы Национального совета по радиационной защите и измерениям США и отечественные методические указания 2.6.1.034-2014 «Порядок взаимодействия предприятий Госкорпорации «Росатом» и органов и организаций ФМБА России при нестандартном (раневом) и аварийном ингаляционном поступлении изотопов плутония и америция-241». Единые требования к порядку выполнения декорпорации в части кратности введения препарата и продолжительности курса декорпорации данными документами не устанавливаются, также не выработан единый подход к определению критерия для принятия решений о применении хелата и об окончании курса декорпорации. В настоящее время, пока не установлены единые критерии для принятия решения о начале декорпорационной терапии, следует руководствоваться принципом оперативности и начинать декорпорацию в кратчайшие сроки после предполагаемого или известного поступления. В дальнейшем тактика декорпорации должна определяться по мере поступления информации об оценках дозиметрических величин, с учетом состояния здоровья пострадавшего работника, не исключая возможность отложенного применения хелата.</p></abstract><trans-abstract xml:lang="en"><p>In conditions of plutonium processing production, despite the achieved improvement of the radiation situation in the workplace, the probability of emergency situations leading to acute inhalation of radionuclides or their entry through damaged skin cannot be ruled out. In such cases, chelates are used to prevent radiation injuries or reduce the risk of their occurrence. The aim of this study was to examine domestic and foreign methodological documents and to determine the degree of completeness and sufficiency of the recommendations contained therein for the decorporation of plutonium and americium with chelate. General recommendations for the use of chelate complexes presented in Publication No. 96 of the International Commission on Radiological Protection, documents of the International Atomic Energy Agency, as well as documents of the National Council on Radiation Protection and Measurements of the United States, and domestic Methodological Guidelines 2.6.1.034-2014 “Order of Interaction between enterprises of State Atomic Energy Corporation “Rosatom” and organs and organizations of FMBA of Russia in case of non-standard (wound) and accidental inhalation intake of plutonium and americium-241 isotopes” were reviewed. Uniform requirements for the procedure for performing decorporation in terms of the frequency of drug administration and the duration of the decorporation course are not established by these documents; also, a uniform approach to determining the criterion for making a decision on the use of a chelate and the end of the decorporation course has not been developed. At present, until uniform criteria for making a decision on the initiation of decorporation therapy have been established, it is proposed to be guided by the principle of promptness and to begin decorporation as soon as possible after the expected or known intake. Then, decorporation tactics should be determined as information on dosimetric assessments becomes available, taking into account the health status of the affected worker, without excluding the possibility of delayed use of the chelate.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>плутоний</kwd><kwd>америций</kwd><kwd>декорпорация</kwd><kwd>хелат</kwd><kwd>пентацин</kwd></kwd-group><kwd-group xml:lang="en"><kwd>plutonium</kwd><kwd>americium</kwd><kwd>decorporation</kwd><kwd>chelate</kwd><kwd>pentacine</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Работа выполнена в рамках Государственного контракта  от 15.06.2025 № 11.314.25.2 «Техногенное облучение и его  отдаленные медицинские последствия» шифр «Последствия 25-27», финансируемого ФМБА России.</funding-statement><funding-statement xml:lang="en">The work was carried out within the framework of the Government contract “Industrial radiation and its long-term medical consequences” and the population of adjacent territories” №11.001.22.800 from 15.06.2025 code “Consequences 25-27”, funded by the Federal Medical and Biological Agency of Russia.</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Rump A., Strickilin D., Lamkowsski A. et al. 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