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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">radhyd</journal-id><journal-title-group><journal-title xml:lang="ru">Радиационная гигиена</journal-title><trans-title-group xml:lang="en"><trans-title>Radiatsionnaya Gygiena = Radiation Hygiene</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1998-426X</issn><issn pub-type="epub">2409-9082</issn><publisher><publisher-name>NIIRG</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21514/1998-426X-2019-12-3-6-15</article-id><article-id custom-type="elpub" pub-id-type="custom">radhyd-637</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Научные статьи</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Scientific articles</subject></subj-group></article-categories><title-group><article-title>Возможность снижения лучевой нагрузки на пациентов за счет оптимизации протокола компьютерной томографии органов брюшной полости и забрюшинного пространства в зависимости от нозологии злокачественного процесса</article-title><trans-title-group xml:lang="en"><trans-title>Prospects for the reduction of the patient doses based on the optimization of the CT abdomen protocols for the different types of malignancies</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Башков</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Bashkov</surname><given-names>A. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Башков Андрей Николаевич – заведующий отделением лучевой и радиоизотопной диагностики, научный сотрудник лаборатории №12</p><p>123098, Москва, ул. Маршала Новикова, д.23</p></bio><bio xml:lang="en"><p>Andrey N. Bashkov – Head of Radiology department; researcher of the Laboratory №12</p><p>ul. Marshala Novikova, 23, Moscow, 123098</p></bio><email xlink:type="simple">abashkov@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шейх</surname><given-names>Ж. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Sheykh</surname><given-names>Zh. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шейх Жанна Владимировна – доктор медицинских наук, профессор кафедры рентгенологии и радиологии, заведующая отделением КТ, ГКБ им. С.П.Боткина </p><p>Москва</p></bio><bio xml:lang="en"><p>Zhanna V. Sheykh – Doct. of med. sci., professor, Head of CT department, City clinical hospital named after S.P. Botkin of the Department of health of Moscow</p><p>Moscow</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Восканян</surname><given-names>С. Э.</given-names></name><name name-style="western" xml:lang="en"><surname>Voskanyan</surname><given-names>S. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Восканян Сергей Эдуардович – доктор медицинских наук, профессор, заместитель главного врача по хирургии – руководитель центра хирургии и трансплантологии, заведующий кафедрой хирургии с курсами онкологии, эндоскопии и хирургической патологии института постдипломного профессионального образования</p><p>Москва</p></bio><bio xml:lang="en"><p>Sergey E. Voskanyan – Doct. of med. sci, Deputy Chief for Surgery, Head of the Center for Surgery and Transplantology, Head of the Department of Surgery with courses of Oncology, Endoscopy of the Institute of postgraduate professional education</p><p>Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дунаев</surname><given-names>А. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Dunaev</surname><given-names>A. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Дунаев Алексей Петрович – кандидат медицинских наук, врач отделения лучевой диагностики</p><p>поселок Истра, Московская область</p></bio><bio xml:lang="en"><p>Aleksey P. Dunaev – Phd. in Med.Sci., radiologist of the radiology department</p><p>Village Istra, Moscow region</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Попов</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Popov</surname><given-names>M. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Попов Максим Васильевич – врач-хирург отделения рентгенохирургических методов диагностики и лечения</p><p>Москва</p></bio><bio xml:lang="en"><p>Maksim V. Popov – surgeon of the department of the endovascular treatment</p><p>Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Удалов</surname><given-names>Ю. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Udalov</surname><given-names>Yu. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Удалов Юрий Дмитриевич – кандидат медицинских наук, доцент, заместитель генерального директора по медицинской части</p><p>Москва</p></bio><bio xml:lang="en"><p>Yuriy D. Udalov – Phd. in Med.Sci., Deputy Chief of general director</p><p>Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Самойлов</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Samoylov</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Самойлов Александр Сергеевич – доктор медицинских наук, доцент, генеральный директор</p><p>Москва</p></bio><bio xml:lang="en"><p>Aleksandr S. Samoylov – Doct. of med. Sci., general director</p><p>Moscow</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Государственный научный центр – Федеральный медико-биофизический центр имени А.И. Бурназяна, Федеральное медико-биологическое агентство России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>State Research Center – Burnasyan Federal Medical Biophysical Center of Federal Medical Biological Agency of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Городская клиническая больница имени С.П. Боткина Департамента здравоохранения г. Москвы; Российская медицинская академия непрерывного профессионального образования, Министерство здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>City clinical hospital named after S.P. Botkin of the Department of health of Moscow; Russian medical Academy of continuing professional education of the Ministry of health of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Московская городская клиническая онкологическая больница № 62 Департамента здравоохранения г. Москвы</institution><country>Россия</country></aff><aff xml:lang="en"><institution>City clinical hospital №62 of the Department of health of Moscow</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>08</day><month>10</month><year>2019</year></pub-date><volume>12</volume><issue>3</issue><fpage>6</fpage><lpage>15</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Башков А.Н., Шейх Ж.В., Восканян С.Э., Дунаев А.П., Попов М.В., Удалов Ю.Д., Самойлов А.С., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Башков А.Н., Шейх Ж.В., Восканян С.Э., Дунаев А.П., Попов М.В., Удалов Ю.Д., Самойлов А.С.</copyright-holder><copyright-holder xml:lang="en">Bashkov A.N., Sheykh Z.V., Voskanyan S.E., Dunaev A.P., Popov M.V., Udalov Y.D., Samoylov A.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.radhyg.ru/jour/article/view/637">https://www.radhyg.ru/jour/article/view/637</self-uri><abstract><p>Снижение лучевой нагрузки при компьютерной томографии является актуальной медицинской задачей в связи с ростом количества исследований и отсутствием общепринятых подходов при повторных исследованиях у онкологических пациентов. В работах различных авторов продемонстрирована целесообразность ограничения протокола компьютерной томографии одной или двумя фазами сканирования при повторных исследованиях у пациентов с онкологическими заболеваниями без потери диагностической информации. В настоящей работе на основе выборки из 514 пациентов были сформированы две группы. В 1 группе (контрольная) пациентам проводилась компьютерная томография органов брюшной полости по трех- или четырехфазному протоколу. Во 2 группе этим же пациентам с интервалом от 1 до 5,5 месяцев проводилась компьютерная томография органов брюшной полости по одноили двухфазному протоколу в зависимости от степени васкуляризации опухолевой ткани и клинической ситуации. При этом было продемонстрировано снижение средней эффективной дозы у пациентов в группе 2 по сравнению с группой 1 на 63% (p&lt;0,05). Во всех случаях различные патологические изменения, характеризующие онкологический процесс и диагностированные при трех- или четырехфазном протоколе, были визуализированы и при одно- или двухфазном протоколе. Таким образом, информативность компьютерной томографии не снижалась.</p></abstract><trans-abstract xml:lang="en"><p>Reducing radiation exposure in computed tomography is a relevant medical task due to the growing number of studies and the lack of generally accepted approaches to their conduct in the radiological community. One way to reduce the effective dose in contrast-enhanced computed tomography of the abdomen is to optimize the protocol of examination, which can include four scans: in the native, arterial, venous and delayed phases. However while providing repeated studies in patients with oncological diseases, it is possible to confine one or two phases, which will allow the radiologist to visualize observed pathological changes and to evaluate the response to the treatment, as well as detect the recurrence in case of the monitoring of the patients. In the present study, two groups were formed on the basis of a sample of 514 patients. In group 1 (control), CTB was performed according to a three- or four-phase protocol. In group 2, the same patients with an interval from 1 to 5.5 months were performed with computed tomography -OBP according to a single or two-phase protocol depending on the degree of vascularization of the tumor tissue and the clinical situation. At the same time, a decrease in the average effective dose in patients in group 2 compared with group 1 was demonstrated by 63% (p&lt;0.05). In all cases, the various pathological changes that characterize the oncological process and were diagnosed with a three- or four-phase protocol were visualized with a single- or two-phase protocol. Thus, the informative value of computed tomography examination did not decrease.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>компьютерная томография</kwd><kwd>лучевая нагрузка</kwd><kwd>эффективная доза</kwd><kwd>оптимизация протокола</kwd><kwd>редукция мультифазного протокола</kwd><kwd>однофазный протокол</kwd><kwd>двухфазный протокол</kwd></kwd-group><kwd-group xml:lang="en"><kwd>computed tomography</kwd><kwd>radiation exposure</kwd><kwd>effective dose</kwd><kwd>optimization of the protocol</kwd><kwd>reducing of the multiphase protocol</kwd><kwd>single-phase protocol</kwd><kwd>dual-phase protocol</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Rehani, M.M. Patient radiation exposure and dose tracking: a perspective. J Med Imaging (Bellingham), 2017, Vol. 4, №3, pp. 031206. doi: 10.1117/1.JMI.4.3.031206.</mixed-citation><mixed-citation xml:lang="en">Rehani, M.M. Patient radiation exposure and dose tracking: a perspective. J Med Imaging (Bellingham), 2017, Vol. 4, №3, pp. 031206. doi: 10.1117/1.JMI.4.3.031206.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Маткевич, Е.И. Сравнительная оценка лучевой нагрузки на пациентов при компьютерной томографии различных анатомических зон: автореф. дисс. … канд. мед. наук / Маткевич Е.И. – Москва, 2017. – 24 с.</mixed-citation><mixed-citation xml:lang="en">Matkevich E.I. Comparative assessment of the patient doses from the computed tomography of various anatomical regions. Abstract of the MD thesis [dissertation]. Moscow; 2017, 24 p. (In Russian)</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Барковский, А.Н. Дозы облучения населения Российской Федерации в 2017 году: информ. сборник / А.Н. Барковский [и др.]. – СПб, 2018.</mixed-citation><mixed-citation xml:lang="en">Barkovsky A.N. [et al.]. Radiation doses of the population of the Russian Federation in 2017: inform. collection. StPetersburg, 2018. (In Russian)</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Балонов, М.И. Современные уровни медицинского облучения в России / М.И. Балонов [и др.] // Радиационная гигиена. – 2015. – Т. 8, № 3. – С. 67–79.</mixed-citation><mixed-citation xml:lang="en">Balonov M.I. [et al.]. Modern levels of medical exposure in Russia. Radiation hygiene, 2015, Vol. 8, № 3, pp. 67–79. (In Russian)</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Маткевич, Е.И. Сравнительный анализ доз облучения пациентов при компьютерной томографии в федеральном лечебном учреждении / E.И. Маткевич, В.Е. Синицын, Е.А. Мершина // Вестник рентгенологии и радиологии. – 2016. – Т. 97, №1. – С. 33-39. doi: 10.20862/0042-4676-2016-97-1-33-40.</mixed-citation><mixed-citation xml:lang="en">Matkevich E.I., Sinitsyn V.E., Mershina E.A. Comparative analysis of the patient doses from computed tomography in a federal healthcare facility. Vestnik rentgenologii i radiologii = Bulletin of rentgenology and radiology, 2016, Vol. 97, №1, pp. 33-39. doi: 10.20862/0042-4676-2016-97-1-33-40. (In Russian)</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Маткевич, Е.И. Сравнение доз облучения пациентов при проведении однофазной и многофазной компьютерной томографии в многопрофильном лечебном учреждении / Е.И. Маткевич, В.Е. Синицын, А.Н. Башков // Медицинская радиология и радиационная безопасность. – 2016. – Т. 61, № 6. – C. 50-56.</mixed-citation><mixed-citation xml:lang="en">Matkevich E.I., Sinitsyn V.E., Bashkov A.N. Comparison of the patient doses from single phase and multiphase computed tomography in a general practice hospital. Meditsinskaya radiologiya i radiatsionnaya bezopasnost = Medical Radiology and Radiation Safety, 2016, Vol. 61, № 6, pp. 50-56. (In Russian)</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Прокоп, М. Спиральная и многослойная компьютерная томография: учебное пособие. В 2 т. / М. Прокоп, М. Галански; пер. с англ.; под ред. А.В. Зубарева, Ш.Ш. Шотемора. – М.: МЕДпресс-информ, 2006. – Т. 1. – 416 с.</mixed-citation><mixed-citation xml:lang="en">Prokop M., Galanski M. Spiral and multilayer computed tomography: a training manual. In 2 Vol. Translation from English; ed. by Zubareva A.V., Shothemor Sh. Sh. Moscow; MED press-inform, 2006, Vol. 1, 416 p. (In Russian)</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Буровик, И.А. Оптимизация спиральной компьютерной томографии при оценке эффективности консервативного лечения онкологических больных: автореф. дисс. … канд. мед. наук / Буровик И.А. – Санкт-Петербург, 2017. – 23 с.</mixed-citation><mixed-citation xml:lang="en">Burovik I.A. Optimization of the helical computed tomography for the assessment of the effectiveness of the conservative treatment of the oncological patients. MD thesis [dissertation]. St-Petersburg; 2017, 23 p. (In Russian)</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Гомболевский, В.А. Низкодозовый протокол компьютерной томографии при лимфоме Ходжкина / В.А. Гомболевский, П.М. Котляров, П.В. Даценко, Н.В. Нуднов // Вестник РНЦРР. – 2013. – №13: https://cyberleninka.ru/article/n/nizkodozovyy-protokol-kompyuternoy-tomografii-pri-limfome-hodzhkina (дата обращения: 21.06.2019).</mixed-citation><mixed-citation xml:lang="en">Gombolevsky V.A., Kotlyarov P.M., Datsenko P.V., Nudnov N.V. Low-dose protocol of computed tomography in Hodgkin’s lymphoma. Vestnik RNCRR, 2013, №13. – Available on: https://cyberleninka.ru/article/n/nizkodozovyy-protokol-kompyuternoy-tomografii-pri-limfome-hodzhkina (Accessed: 21.06.2019). (In Russian)</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Хасанова, К.А. Снижение дозовой нагрузки при проведении компьютерной томографии у детей / К.А. Хасанова, И.Е. Тюрин, С.А. Рыжков, Е.В. Кижаев // Медицинская радиология и радиационная безопасность. – 2019. – Т. 64, № 1. – С. 38-44.</mixed-citation><mixed-citation xml:lang="en">Khasanova K.A., Tyurin I.E., Ryzhkov S.A., Kizhaev E.V. Reduction of dose load during computed tomography in children. Meditsinskaya radiologiya i radiatsionnaya bezopasnost = Medical Radiology and Radiation Safety, 2019, Vol. 64, № 1, pp. 38-44. (In Russian)</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Морозов, С.П. Мультиспиральная компьютерная томография в многопрофильном стационаре / С.П. Морозов, И.Ю. Насникова, С.К. Терновой. – Москва, 2009. – 249 с.</mixed-citation><mixed-citation xml:lang="en">Morozov S.P., Nasnikova I.Yu., Ternovoy S.K. Multispiral computed tomography in a multidisciplinary hospital. Moscow, 2009. – 249 p. (In Russian)</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">K.M. Guite, J.L. Hinshaw, F.N. Ranallo, M.J. Lindstrom, Lee FT Jr.J. Ionizing radiation in abdominal CT: unindicated multiphase scans are an important source of medically unnecessary exposure. Am. Coll. Radiol., 2011, Vol.8, №11, pp. 756-61. doi: 10.1016/j.jacr.2011.05.011.</mixed-citation><mixed-citation xml:lang="en">K.M. Guite, J.L. Hinshaw, F.N. Ranallo, M.J. Lindstrom, Lee FT Jr.J. Ionizing radiation in abdominal CT: unindicated multiphase scans are an important source of medically unnecessary exposure. Am. Coll. Radiol., 2011, Vol.8, №11, pp. 75661. doi: 10.1016/j.jacr.2011.05.011.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Luigi Camera, Immacolata Liccardo, Federica Romano, Raffaele Liuzzi [et al.] Diagnostic efficacy of single-pass abdominal multidetector-row CT: prospective evaluation of a low dose protocol. Br. J. Radiol., 2017, Vol.90(1070): 20160612. Published online 2017 Jan 10. doi: 10.1259/bjr.20160612.</mixed-citation><mixed-citation xml:lang="en">Luigi Camera, Immacolata Liccardo, Federica Romano, Raffaele Liuzzi [et al.] Diagnostic efficacy of single-pass abdominal multidetector-row CT: prospective evaluation of a low dose protocol. Br. J. Radiol., 2017, Vol.90(1070): 20160612. Published online 2017 Jan 10. doi: 10.1259/bjr.20160612.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Costa Danilo, Manuel Cerqueira [et al.] When the noncontrast-enhanced phase is unnecessary in abdominal computed tomography scans? A retrospective analysis of 244 cases. Radiol. Bras., 2013, 46(4):197-202. http://dx.doi.org/10.1590/S0100-39842013000400004.</mixed-citation><mixed-citation xml:lang="en">Costa Danilo, Manuel Cerqueira [et al.] When the non-contrast-enhanced phase is unnecessary in abdominal computed tomography scans? A retrospective analysis of 244 cases. Radiol. Bras., 2013, 46(4):197-202. http://dx.doi.org/10.1590/S0100-39842013000400004.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Waszczuk Ł ., Guziński M., Garcarek J., Sąsiadek M. Triplephase abdomen and pelvis computed tomography: standard unenhanced phase can be replaced with reduced-dose scan. Polish Journal of Radiology, 2018, №83, pp. 166-170. doi:10.5114/pjr.2018.75682.</mixed-citation><mixed-citation xml:lang="en">Waszczuk  Ł ., Guziński M., Garcarek J., Sąsiadek M. Triplephase abdomen and pelvis computed tomography: standard unenhanced phase can be replaced with reduced-dose scan. Polish Journal of Radiology, 2018, №83, pp. 166-170. doi:10.5114/pjr.2018.75682.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Jing-Feng Zhang, Guo Chuan-Gen, Liao Jin-Sheng, Wang Qi-Dong [et al.] Abdominal CT protocol’s influence on postoperative follow-up of lesions detection associated with gastrointestinal tumors. TCR, 2017, Vol.6, №6, pp. 11231128. doi:10.1007/s10140-018-1591-1.</mixed-citation><mixed-citation xml:lang="en">Jing-Feng Zhang, Guo Chuan-Gen, Liao Jin-Sheng, Wang Qi-Dong [et al.] Abdominal CT protocol’s influence on postoperative follow-up of lesions detection associated with gastrointestinal tumors. TCR, 2017, Vol.6, №6, pp. 1123-1128. doi: 10.1007/s10140-018-1591-1.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Pamela Johnson [et al.] New ACR Choosing Wisely Recommendations: Judicious Use of Multiphase Abdominal CT Protocols. Journal of the American College of Radiology, 2018, Vol.16, №1, pp. 56-60. doi: 10.1016/j.jacr.2018.07.026.</mixed-citation><mixed-citation xml:lang="en">Pamela Johnson [et al.] New ACR Choosing Wisely Recommendations: Judicious Use of Multiphase Abdominal CT Protocols. Journal of the American College of Radiology, 2018, Vol.16, №1, pp. 56-60. doi: 10.1016/j.jacr.2018.07.026.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Jeavons C., Hacking C., Beenen L.F., Gunn M.L. A review of split-bolus single-pass CT in the assessment of trauma patients. Emerg. Radiol., 2018, Vol.25, №4, pp. 367-374. doi: 10.1007/s10140-018-1591-1.</mixed-citation><mixed-citation xml:lang="en">Jeavons C., Hacking C., Beenen L.F., Gunn M.L. A review of split-bolus single-pass CT in the assessment of trauma patients. Emerg. Radiol., 2018, Vol.25, №4, pp. 367-374. doi: 10.1007/s10140-018-1591-1.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Kim Y.H., Kim M.J., Shin H.J., Yoon H., Lee M.J. Simplified split-bolus intravenous contrast injection technique for pediatric abdominal CT. Clin. Imaging, 2017, №46, pp. 2832. doi: 10.1016/j.clinimag.2017.06.002.</mixed-citation><mixed-citation xml:lang="en">Kim Y.H., Kim M.J., Shin H.J., Yoon H., Lee M.J. Simplified split-bolus intravenous contrast injection technique for pediatric abdominal CT. Clin. Imaging, 2017, №46, pp. 28-32. doi: 10.1016/j.clinimag.2017.06.002.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Klaus Tatsch, Wolfgang Eschner, Fred J. Verzijlbergen, Sally F. Barrington [et al.] FDG PET/CT: EANM procedure guidelines for tumour imaging: version 2.0. Eur. J. Nucl. Med. Mol. Imaging, 2015, №42, pp. 328–354. DOI 10.1007/s00259-014-2961.</mixed-citation><mixed-citation xml:lang="en">Klaus Tatsch, Wolfgang Eschner, Fred J. Verzijlbergen, Sally F. Barrington [et al.] FDG PET/CT: EANM procedure guidelines for tumour imaging: version 2.0. Eur. J. Nucl. Med. Mol. Imaging, 2015, №42, pp. 328–354. DOI 10.1007/s00259-014-2961.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Roland Bares, Claus D. Claussen and Anna C. Pfannenberg Klaus Brechtel, Magnus Klein, Monika Vogel, Marc Mueller, Philip Aschoff, Thomas Beyer, Susanna M. Eschmann. PET/ CT: Technical Aspects of Single-Phase Versus Multiphase CT Imaging Optimized Contrast-Enhanced CT Protocols for Diagnostic Whole-Body 18F-FDG. J. Nucl. Med., 2006, №47, pp. 470-476.</mixed-citation><mixed-citation xml:lang="en">Roland Bares, Claus D. Claussen and Anna C. Pfannenberg Klaus Brechtel, Magnus Klein, Monika Vogel, Marc Mueller, Philip Aschoff, Thomas Beyer, Susanna M. Eschmann. PET/ CT: Technical Aspects of Single-Phase Versus Multiphase CT Imaging Optimized Contrast-Enhanced CT Protocols for Diagnostic Whole-Body 18F-FDG. J. Nucl. Med., 2006, №47, pp. 470-476.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Silvia Morbelli, Raffaella Conzi, Claudio Campus, Giuseppe Cittadini [et al.] Contrast-enhanced [18 F] fluorodeoxyglucose-positron emission tomography/ computed tomography in clinical oncology: tumor-, site-, and question-based comparison with standard positron emission tomography/computed tomography. Cancer Imaging, 2014, 14:10. https://doi.org/10.1186/1470-7330-14-10.</mixed-citation><mixed-citation xml:lang="en">Silvia  Morbelli,  Raffaella  Conzi,  Claudio  Campus, Giuseppe Cittadini [et al.] Contrast-enhanced [18 F] fluorodeoxyglucose-positron  emission  tomography/computed tomography in clinical oncology: tumor-, site-, and questionbased comparison with standard positron emission tomography/computed tomography. Cancer Imaging, 2014, 14:10. https://doi.org/10.1186/1470-7330-14-10.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Смолярчук, Я.М. / Рекомендации по проведению и описанию исследований ПЭТ/КТ с 18F-дезоксиглюкозой, проводимых за счет средств МГФОМС в рамках территориальной программы города Москвы. Методические рекомендации №39а // Я.М. Смолярчук, О.А. Агафонова, С.П. Морозов. – Москва, 2017. – 26 с.</mixed-citation><mixed-citation xml:lang="en">Smolyarchuk  Ya.M.,  Agafonov  O.A.,  Morozov  S.P. Recommendations for the conduct and description of PET/ CT studies with 18F-deoxyglucose carried out at the expense of mgfoms within the territorial program of the city of Moscow. Guidelines No. 39A. Moscow, 2017. (In Russian)</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Труфанов, Г.Е. Совмещённая позитронно-эмиссионная и компьютерная томография в характеристике рецидивов злокачественных новообразований органов грудной клетки и брюшной полости / Г.Е. Труфанов, И.В. Бойков, В.В. Рязанов, В.В. Ипатов // Трансляционная медицина. – 2016. – Т.3. – №5. – С . 95-102. https://doi.org/10.18705/2311-4495-2016-3-5-95-102.</mixed-citation><mixed-citation xml:lang="en">Trufanov G.E., Boikov I.V., Ryazanov V.V., Ipatov V.V. Combined positron emission and computed tomography in the characteristics of relapses of malignant neoplasms of the chest and abdomen. Translyatsionnaya meditsina = Translational medicine, 2016, Vol.3, №5, pp. 95-102. https://doi.org/10.18705/2311-4495-2016-3-5-95-102.  (In Russian)</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Официальный сайт национальной онкологической сети (NCCN): https://www.nccn.org/professionals/physician_gls/recently_updated.aspx / (дата обращения 21.06.2019г.).</mixed-citation><mixed-citation xml:lang="en">The official site of the National Comprehensive Cancer Network (NCCN). – Available on: https://www.nccn.org/professionals/physician_gls/recently_updated.aspx/ (Accessed: 21.06.2019) (In Russian)</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
