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Precautions for certain categories of individuals in contact with a patient after radionuclide therapy

https://doi.org/10.21514/1998-426X-2025-18-1-59-69

Abstract

   Patients undergoing radionuclide therapy with radiopharmaceuticals may become a radiation source of external exposure. Release of the patients requires strict abidance of radiation safety regulations to minimize exposure to individuals in contact with patient, especially children and pregnant women.

   The purpose of the current study was to determine precautions for patients after radionuclide therapy to limit the contact time with others and to develop guidelines to reduce doses to individuals in contact with patient.

   Two cases were considered for analysis: contact with young children and co-sleeping with partners. Determination of the necessary time limitations was performed using open-assessed publications and Monte Carlo calculations at different distances from the patient. The results showed that radionuclide therapy with 225Ac, 223Ra, 89Sr, and 90Y would not exceed the limit of 0.3 mSv to individuals in contact with patient after radionuclide therapy, even in the case of no precautions. However, for patients with 131I, 177Lu and 153Sm, precautions to limit the time of close contact with children and co-sleeping with partners are required. The suggested precautions ensure the radiation safety of individuals in contact with the patient after radionuclide therapy by limiting the exposure limits and allow patients to maintain social contacts, which is important for their rehabilitation.

About the Authors

L. A. Chipiga
Saint Petersburg Research Institute of Radiation Hygiene after Professor P.V. Ramzaev, Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing; A. Granov Russian Scientific Center of Radiology and Surgical Technologies of the Ministry of Health of the Russian Federation; Almazov National Medical Research Centre of the Ministry of Health of the Russian Federation
Russian Federation

Larisa A. Chipiga, Candidate of Engineering Sciences, Research Fellow, Docent

197101; Mira Str., 8; Saint Petersburg



A. V. Likhacheva
Saint Petersburg Research Institute of Radiation Hygiene after Professor P.V. Ramzaev, Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing; The City Hospital No 40 of the Kurortny District
Russian Federation

Anastasia V. Likhacheva, Acting Junior Researcher, Radiation Safety Engineer

Saint Petersburg



I. A. Zvonova
Saint Petersburg Research Institute of Radiation Hygiene after Professor P.V. Ramzaev, Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing
Russian Federation

Irina A. Zvonova, Doctor of Engineering Sciences, Chief Researcher

Protection Laboratory

Saint Petersburg



A. V. Vodovatov
Saint Petersburg Research Institute of Radiation Hygiene after Professor P.V. Ramzaev, Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing; Saint Petersburg State Pediatric Medical University
Russian Federation

Aleksandr V. Vodovatov, Candidate of Biological Sciences, Head of Laboratory, Docent

Saint Petersburg



O. Yu. Toskin
European Medical Center
Russian Federation

 Oleg Yu. Toskin, Head of Department

Radiation Safety Department

Moscow



A. A. Sapelnikov
European Medical Center
Russian Federation

Aleksandr A. Sapelnikov, Radiation Safety Engineer

Moscow



K. S. Velichkina
Technical Scientific Centre for Safety Assessment of RM Packages
Russian Federation

Kristina S. Velichkina, Engineer

Saint Petersburg



A. S. Terenteva
Technical Scientific Centre for Safety Assessment of RM Packages
Russian Federation

Anastasia S. Terenteva, Engineer

Saint Petersburg



A. A. Stanzhevsky
A. Granov Russian Scientific Center of Radiology and Surgical Technologies of the Ministry of Health of the Russian Federation
Russian Federation

Andrey A. Stanzhevsky, Doctor of Medical Sciences, Deputy Director for Research

Saint Petersburg



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Review

For citations:


Chipiga L.A., Likhacheva A.V., Zvonova I.A., Vodovatov A.V., Toskin O.Yu., Sapelnikov A.A., Velichkina K.S., Terenteva A.S., Stanzhevsky A.A. Precautions for certain categories of individuals in contact with a patient after radionuclide therapy. Radiatsionnaya Gygiena = Radiation Hygiene. 2025;18(1):59-69. (In Russ.) https://doi.org/10.21514/1998-426X-2025-18-1-59-69

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ISSN 1998-426X (Print)
ISSN 2409-9082 (Online)